Is Ranidine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Ranidine? Is Ranidine safe for nursing mother and child? Does Ranidine extracts into breast milk? Does Ranidine has any long term or short term side effects on infants? Can Ranidine influence milk supply or can Ranidine decrease milk supply in lactating mothers?

Drug which is commonly used in pediatric therapy even for newborn treatment. Excreted in high amount into breast milk although infant intake is reportedly lower than usual therapeutic dose. No side effects on breastfed babies have been reported. Increase of Prolactin levels has been shown, yet it does not induce galactorrhea.

Although interpatient variability exists, the dose of Ranidine in breastmilk is less than the dose used in newborn infants. Maternal Ranidine would not be expected to cause any adverse effects in breastfed infants. No special precautions are required.

One 54-day-old breastfed infant had no observable adverse effects after maternal ingestion of Ranidine 150 mg every 12 hours for 2 days.[2]

Histamine H2-receptor blockade is known to stimulate prolactin secretion.[3] Ranidine in intravenous doses over 100 mg or during long-term oral use have increased serum prolactin in some studies, and rare cases of gynecomastia have been reported.[4][5][6][7][8] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.