Question

I am a breastfeeding mother and i want to know if it is safe to use 3-Hydroxydiazepam? Is 3-Hydroxydiazepam safe for nursing mother and child? Does 3-Hydroxydiazepam extracts into breast milk? Does 3-Hydroxydiazepam has any long term or short term side effects on infants? Can 3-Hydroxydiazepam influence milk supply or can 3-Hydroxydiazepam decrease milk supply in lactating mothers?

3-Hydroxydiazepam lactation summary

3-Hydroxydiazepam usage has low risk in breastfeeding
  • DrLact safety Score for 3-Hydroxydiazepam is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of 3-Hydroxydiazepam may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that 3-Hydroxydiazepam may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of 3-Hydroxydiazepam low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using 3-Hydroxydiazepam We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 3-Hydroxydiazepam usage in lactation

Eventual and low doses of benzodiazepine are compatible with breastfeeding. Use a short-acting benzodiazepine and minimal effective dose as possible mostly in neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About 3-Hydroxydiazepam usage in lactation

Because of the low levels of 3-Hydroxydiazepam in breastmilk and its relatively short half-life, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants. Taking the bedtime dose after the infant's last feeding of the day may minimize the dose received by an older infant who is sleeping through the night.

3-Hydroxydiazepam Side Effects in Breastfeeding

Ten infants who less than 15 days old were breastfed by mothers who had taken 3-Hydroxydiazepam 10 or 20 mg (0.16 to 0.32 mg/kg) at bedtime once daily for at least 2 days. None of the infants had any observable adverse reactions.[2] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. One mother took 3-Hydroxydiazepam while breastfeeding and reported no sedation in her infant.[3]

3-Hydroxydiazepam Possible Effects in Breastfeeding

Relevant published information was not found as of the revision date..

Alternate Drugs

Lorazepam(Safe)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Estazolam(Low Risk)
Flurazepam(Unsafe)
Temazepam(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Estazolam(Low Risk)
Zolpidem(Safe)
Zaleplon(Safe)
Flurazepam(Unsafe)
Lorazepam(Safe)
Triazolam(Low Risk)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Butabarbital(Low Risk)
Quazepam(Unsafe)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Phenobarbital(Low Risk)
Secobarbital(Low Risk)
Propofol(Safe)
Oxazepam(Safe)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Chloral Hydrate(Low Risk)
Midazolam(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.