Question

I am a breastfeeding mother and i want to know if it is safe to use Cidofovir (Topical Use)? Is Cidofovir (Topical Use) safe for nursing mother and child? Does Cidofovir (Topical Use) extracts into breast milk? Does Cidofovir (Topical Use) has any long term or short term side effects on infants? Can Cidofovir (Topical Use) influence milk supply or can Cidofovir (Topical Use) decrease milk supply in lactating mothers?

Cidofovir (Topical Use) lactation summary

Cidofovir (Topical Use) usage has low risk in breastfeeding
  • DrLact safety Score for Cidofovir (Topical Use) is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Cidofovir (Topical Use) may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Cidofovir (Topical Use) may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Cidofovir (Topical Use) low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Cidofovir (Topical Use) We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Cidofovir (Topical Use) usage in lactation

Used for treatment of CMV retinitis in HIV patients. Toxic effect on kidney function Topically used for intralesional treatment of recurrent laringeal papillomatosis caused by the Human Papilloma Virus, even in infants and children, without side effects. Serum level after intralesional injection varies from 0 to 0.4 mg/L, which is fifty times lower than after intravenous administration. Excretion into breast milk is unknown but absorption by the intestine should be very poor.

Alternate Drugs for Antivirals for topical use. ATC D06BB

Penciclovir(Safe)
Idoxuridine(Safe)
Imiquimod(Safe)
Podophyllotoxin(Low Risk)
Podofilox(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.