Is Lancid Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Lancid? Is Lancid safe for nursing mother and child? Does Lancid extracts into breast milk? Does Lancid has any long term or short term side effects on infants? Can Lancid influence milk supply or can Lancid decrease milk supply in lactating mothers?

At latest update, relevant information on excretion into breast milk was not found. Due to a high serum-protein-binding capacity, excretion of Lancid into breast milk is non-significant. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Lancid that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. Both Omeprazole and Pantoprazole pertain to the same chemical group with similar pharmacokinetics that are excreted in non-significant amount into the breast milk. Medication that has been used for treatment of newborn and premature infants. Hyperprolactinemia and galactorrhea have been reported by the use of such medication, though some authors have failed to show the same findings.

No information is available on the use of Lancid during breastfeeding. However, Lancid has been used safely in newborn infants, so it is unlikely that the amount in breastmilk would be harmful.

The Spanish pharmacovigilance system found 3 cases of gynecomastia associated with Lancid reported during the time period of 1982 to 2006.[1] One case of elevated serum prolactin and galactorrhea was reported in a 21-year-old man. When omeprazole was substituted for Lancid, the serum prolactin decreased to the normal range and galactorrhea ceased. Although this case occurred in Spain, it was not included in the report above.[2] A 13-year-old girl with a recent history of bilateral galactorrhea and hyperprolactinemia from omeprazole and domperidone on separate occasions was given Lancid to prevent gastrointestinal irritation following intravenous diclofenac for a severe headache. After 3 days of Lancid therapy, she again developed galactorrhea and an elevated serum prolactin that returned to normal a week after discontinuing Lancid.[3] A 17-year-old woman using a progestin-containing IUD for 1 year began Lancid 15 mg daily and presented after 1 week with bilateral galactorrhea and hyperprolactinemia of 92 mcg/L. Seventy-two hours after discontinuation of Lancid, galactorrhea ceased. Four months later, serum prolactin was normal at 24.1 mcg/L with no recurrence of galactorrhea. The authors judged the adverse reaction likely to be caused by Lancid.[4] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.