Is N-(2-Hydroxyethyl)-1-deoxynojirimycin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-(2-Hydroxyethyl)-1-deoxynojirimycin? Is N-(2-Hydroxyethyl)-1-deoxynojirimycin safe for nursing mother and child? Does N-(2-Hydroxyethyl)-1-deoxynojirimycin extracts into breast milk? Does N-(2-Hydroxyethyl)-1-deoxynojirimycin has any long term or short term side effects on infants? Can N-(2-Hydroxyethyl)-1-deoxynojirimycin influence milk supply or can N-(2-Hydroxyethyl)-1-deoxynojirimycin decrease milk supply in lactating mothers?
N-(2-Hydroxyethyl)-1-deoxynojirimycin lactation summary
- DrLact safety Score for N-(2-Hydroxyethyl)-1-deoxynojirimycin is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N-(2-Hydroxyethyl)-1-deoxynojirimycin is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N-(2-Hydroxyethyl)-1-deoxynojirimycin does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N-(2-Hydroxyethyl)-1-deoxynojirimycin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-(2-Hydroxyethyl)-1-deoxynojirimycin usage in lactation
Alpha-glucosidase inhibitor which acts within the gastrointestinal tract without being absorbed, reducing intestinal absorption of glucose. Very low risk of hypoglycemia in monotherapy. N-(2-Hydroxyethyl)-1-deoxynojirimycin is excreted in breast milk in minute quantities (Serrano 2014, Pfizer 2012, AEMPS 2009) reaching a relative dose much less than 1%. Diet, exercise, and breastfeeding improve blood sugar levels.
Answer by DrLact: About N-(2-Hydroxyethyl)-1-deoxynojirimycin usage in lactation
Limited data indicate that N-(2-Hydroxyethyl)-1-deoxynojirimycin is poorly excreted into breastmilk. Because N-(2-Hydroxyethyl)-1-deoxynojirimycin is also poorly absorbed orally, it is unlikely to adversely affect the breastfed infant.
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