Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7292? Is HSDB 7292 safe for nursing mother and child? Does HSDB 7292 extracts into breast milk? Does HSDB 7292 has any long term or short term side effects on infants? Can HSDB 7292 influence milk supply or can HSDB 7292 decrease milk supply in lactating mothers?

HSDB 7292 lactation summary

HSDB 7292 is safe in breastfeeding
  • DrLact safety Score for HSDB 7292 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 7292 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 7292 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 7292 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7292 usage in lactation

Due to a high serum-protein-binding capacity, excretion into breast milk is non-significant without side-effects among breastfed infants from treated mothers. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of HSDB 7292 that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. No effect on Prolactin secretion has been observed. Other formulations of HSDB 7292 without anti-acid protection are destroyed in the stomach.

Answer by DrLact: About HSDB 7292 usage in lactation

Maternal HSDB 7292 doses of 40 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.