Is apo-Pantoprazole Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use apo-Pantoprazole? Is apo-Pantoprazole safe for nursing mother and child? Does apo-Pantoprazole extracts into breast milk? Does apo-Pantoprazole has any long term or short term side effects on infants? Can apo-Pantoprazole influence milk supply or can apo-Pantoprazole decrease milk supply in lactating mothers?
apo-Pantoprazole lactation summary
- DrLact safety Score for apo-Pantoprazole is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of apo-Pantoprazole is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that apo-Pantoprazole does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of apo-Pantoprazole safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About apo-Pantoprazole usage in lactation
Due to a high serum-protein-binding capacity, excretion into breast milk is non-significant without side-effects among breastfed infants from treated mothers. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of apo-Pantoprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. No effect on Prolactin secretion has been observed. Other formulations of apo-Pantoprazole without anti-acid protection are destroyed in the stomach.
Answer by DrLact: About apo-Pantoprazole usage in lactation
Maternal apo-Pantoprazole doses of 40 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants.
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