Is Habeprazole Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Habeprazole? Is Habeprazole safe for nursing mother and child? Does Habeprazole extracts into breast milk? Does Habeprazole has any long term or short term side effects on infants? Can Habeprazole influence milk supply or can Habeprazole decrease milk supply in lactating mothers?

At latest update, relevant information on excretion into breast milk was not found. Due to a high serum-protein-binding capacity, excretion of Habeprazole into breast milk in significant levels is unlikely. Since it's neutralized by the acid pH of stomach, capsules with enteric coated granules are used. Because of this, it is thought that the small quantity of Habeprazole that may reach the breast milk would be neutralized by infant's stomach. In addition, absorption is greatly decreased by the presence of food. Both Omeprazole and Pantoprazole pertain to the same chemical group with similar pharmacokinetics that are excreted in non-significant amount into the breast milk. No alteration on serum Prolactin level has been shown.

Because no information is available on the use of Habeprazole during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

The Spanish pharmacovigilance system found one case of a 90-year-old man who developed gynecomastia associated with Habeprazole reported during the time period of 1982 to 2006. The reaction occurred after 32 days of therapy and resolved after discontinuation of the drug.[1]