Is Astemizole Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Astemizole? Is Astemizole safe for nursing mother and child? Does Astemizole extracts into breast milk? Does Astemizole has any long term or short term side effects on infants? Can Astemizole influence milk supply or can Astemizole decrease milk supply in lactating mothers?

Astemizole lactation summary

DrLact safety Score for Astemizole is 5 out of 8 which is considered Unsafe as per our analyses.
A safety Score of 5 indicates that usage of Astemizole may cause serious side effects in breastfed baby.
Our study of different scientific research indicates that Astemizole may cause moderate to high side effects or may affect milk supply in lactating mother.
Our suggestion is to use safer alternate options rather than using Astemizole .
It is recommended to evaluate the advantage of not breastfeeding while using Astemizole Vs not using Astemizole And continue breastfeeding.
While using Astemizole Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Astemizole usage in lactation

Second generation anti-histaminic and pyperidine drug with a slightly sedative effect.Withdrawn from the market in Spain because of an increased risk of ventricular arrhytmias

Alternate Drugs for Antihistamines for systemic use. ATC R06A.

Acrivastine(Low Risk)

Brompheniramine(Low Risk)

Carbinoxamine(Low Risk)

Cetirizine(Safe)

Chlorpheniramine(Low Risk)

Clemastine(Low Risk)

Desloratadine(Safe)

Dexchlorpheniramine(Low Risk)

Dimenhydrinate(Low Risk)

Diphenhydramine(Low Risk)

Fexofenadine(Safe)

Hydroxyzine(Safe)

Loratadine(Safe)

Promethazine(Low Risk)

Pyrilamine(Low Risk)

Thiethylperazine(Unsafe)

Triprolidine(Safe)

Epinastine(Low Risk)

Meclizine(Low Risk)

Ketotifen(Low Risk)

Levocetirizine(Low Risk)

Cyclizine(Low Risk)

Doxylamine(Unsafe)

Cetirizine Hydrochloride(Safe)

Alimemazine(Low Risk)

Azatadine Maleate(Low Risk)

Bilastine(Low Risk)

Brompheniramine Maleate(Low Risk)

Buclizine-Hcl(Low Risk)

Carbinoxamine Maleate(Low Risk)

Cyproheptadine-Hcl(Low Risk)

Clemastine Fumarate(Low Risk)

Chlorcyclizine(Low Risk)

Chlorphenamine(Low Risk)

Chloropyramine Hydrochloride(Unsafe)

Ebastine(Low Risk)

Fexofenadine Hydrochloride(Safe)

Ketotifen Fumarate(Low Risk)

Meclozine(Low Risk)

Mepyramine(Low Risk)

Mequitazine(Unsafe)

Mizolastine(Low Risk)

Pizotifen(Low Risk)

Rupatadine Fumarate(Low Risk)

Terfenadine(Low Risk)

Triprolidine Hydrochloride(Safe)

Dimetindene Maleate (systemic use)(Unsafe)

Trimeprazine(Low Risk)

Halopyramine Hydrochloride(Unsafe)

Doxylamine Succinate(Unsafe)

Dramamine Ii(Low Risk)

Chlorpheniramine Maleate(Low Risk)

Pizotyline(Low Risk)

Benzhydramine(Low Risk)

Promethazine Hydrochloride(Low Risk)

Pyranisamine(Low Risk)

Kelp(Unsafe)

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.