Question

I am a breastfeeding mother and i want to know if it is safe to use Dimetindene Maleate (systemic use)? Is Dimetindene Maleate (systemic use) safe for nursing mother and child? Does Dimetindene Maleate (systemic use) extracts into breast milk? Does Dimetindene Maleate (systemic use) has any long term or short term side effects on infants? Can Dimetindene Maleate (systemic use) influence milk supply or can Dimetindene Maleate (systemic use) decrease milk supply in lactating mothers?

Dimetindene Maleate (systemic use) lactation summary

Dimetindene Maleate (systemic use) is unsafe in breastfeeding
  • DrLact safety Score for Dimetindene Maleate (systemic use) is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Dimetindene Maleate (systemic use) may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Dimetindene Maleate (systemic use) may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Dimetindene Maleate (systemic use) .
  • It is recommended to evaluate the advantage of not breastfeeding while using Dimetindene Maleate (systemic use) Vs not using Dimetindene Maleate (systemic use) And continue breastfeeding.
  • While using Dimetindene Maleate (systemic use) Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dimetindene Maleate (systemic use) usage in lactation

First generation antihistamine drug which is derived from ethylene diamine with important sedative and antimuscarinic effects. At latest update no published data on excretion into breast milk was found.Inhibition of breastfeeding in the first weeks after birth due to an antiprolactin effect may appear.For both the mother and the infant it would be safer taking antihistamines with proven safety and without sedative effect, especially in case of premature babies and infants under 1 month of age. Otherwise when used during lactation, take the lowest effective dose but avoiding a prolonged use. Follow-up the baby for drowsiness and feeding issues.It is not recommended to share a bed with your baby if you are taking this medicine. The topical use as a gel or cream is compatible with breastfeeding. Do not apply on the chest. See Dimethindene Maleate (topical).

Alternate Drugs for Antihistamines for systemic use. ATC R06A.

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