I am a breastfeeding mother and i want to know if it is safe to use Proteases? Is Proteases safe for nursing mother and child? Does Proteases extracts into breast milk? Does Proteases has any long term or short term side effects on infants? Can Proteases influence milk supply or can Proteases decrease milk supply in lactating mothers?

Proteases lactation summary

Proteases is safe in breastfeeding
  • DrLact safety Score for Proteases is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Proteases is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Proteases does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Proteases safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Proteases usage in lactation

Enzymes which are able to hydrolyze proteins.They are found in all living beings and are an important part of pancreatic enzymes.They are orally used for gastrointestinal disorders and topically on wounds and burns. There is an increasing trend on type and therapeutic uses (Craik 2011). At latest update relevant published data on excretion into breast milk were not found. Because the small dose used and low plasma uptake of most topical dermatological preparations it is unlikely that significant amounts of it will pass into breastmilk.Its high molecular weight turns further improbable any excretion into breastmilk.Due to its protein nature, when orally taken it is digested by the infant’s intestine, hence its absorption and passage to plasma should be nil. Few studies with low levels of evidence on oral use of protease to alleviate breast congestion have shown uneven results (ABM 2016, Mangesi 2016).

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

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