Question

I am a breastfeeding mother and i want to know if it is safe to use Trientine Dihydrochloride? Is Trientine Dihydrochloride safe for nursing mother and child? Does Trientine Dihydrochloride extracts into breast milk? Does Trientine Dihydrochloride has any long term or short term side effects on infants? Can Trientine Dihydrochloride influence milk supply or can Trientine Dihydrochloride decrease milk supply in lactating mothers?

Trientine Dihydrochloride lactation summary

Trientine Dihydrochloride usage has low risk in breastfeeding
  • DrLact safety Score for Trientine Dihydrochloride is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Trientine Dihydrochloride may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Trientine Dihydrochloride may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Trientine Dihydrochloride low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Trientine Dihydrochloride We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Trientine Dihydrochloride usage in lactation

Copper chelator used in the treatment of Wilson's disease. It is excreted in breast milk in clinically insignificant amounts (undetectable levels: Izumi 2012). Copper and zinc levels in breastmilk of mothers treated with penicillamine, trientine or zinc are normal (Izumi 2012). Oral bioavailability, which is very low during periods of fasting, is practically non-existent in the presence of food, especially milk, so it would be very difficult to pass into the infant plasma from the ingested breast milk (PDR 2016).

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

Levocarnitine(Safe)
Laronidase(Low Risk)
Ademetionine(Safe)
Alpha-Galactosidase(Safe)
Carnitine(Safe)
Phenylbutyrate(Safe)
Lysine(Safe)
Pancreatin(Safe)
Arginine(Safe)
Lactase(Safe)
Anhydrous Citric Acid(Safe)
Branched-Chain Amino Acids (BCAAs)(Safe)
Tryptophan(Low Risk)
Proteases(Safe)
Lipoic Acid(Low Risk)
Serrapeptase(Low Risk)
Lysine Acetate(Safe)
Lysine Hydrochloride(Safe)
Serratiopeptidase(Low Risk)
Arginine Hydrochloride(Safe)
Citric Acid Monohydrate(Safe)
Tilactase(Safe)
L-Tryptophan(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.