Is Sulfamethoxazolum [INN-Latin] Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Sulfamethoxazolum [INN-Latin]? Is Sulfamethoxazolum [INN-Latin] safe for nursing mother and child? Does Sulfamethoxazolum [INN-Latin] extracts into breast milk? Does Sulfamethoxazolum [INN-Latin] has any long term or short term side effects on infants? Can Sulfamethoxazolum [INN-Latin] influence milk supply or can Sulfamethoxazolum [INN-Latin] decrease milk supply in lactating mothers?

Excreted in non-significant levels into breast milk. No adverse effects have been shown in breastfed infants. Caution with those neonates suffering of hyperbilirrubinemia or G-6-P-D deficiency is required. Avoid use in affected patients Check-up for infant jaundice. Be aware of false negative results of bacterial cultures when the mother is on antibiotics. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

With healthy, fullterm infants it appears acceptable to use Sulfamethoxazolum [INN-Latin] during breastfeeding after the newborn period. The time of greatest risk for hemolysis in fullterm newborns without glucose-6-phosphate dehydrogenase (G6PD) deficiency might be as short as 8 days after birth.[1] Until further data are accumulated, alternate agents should probably be used in jaundiced, ill, stressed or premature infants, because of the risk of bilirubin displacement and kernicterus. Sulfamethoxazolum [INN-Latin] should be avoided while breastfeeding a G6PD deficient infant.[2]

An extensive systematic review of the use of sulfonamides near term and during breastfeeding found no adverse reactions in infants. The authors concluded that use of Sulfamethoxazolum [INN-Latin] during breastfeeding presents no risk of neonatal kernicterus.[4] A prospective, controlled study asked mothers who called an information service about adverse reactions experience by their breastfed infants. Of 12 women who took Sulfamethoxazolum [INN-Latin] and trimethoprim during breastfeeding (time postpartum and dosage not reported), none reported diarrhea, drowsiness or irritability in her infant. Two mothers reported poor feeding in their infants.[5]