Question

I am a breastfeeding mother and i want to know if it is safe to use Fluorouracil Topical Solution? Is Fluorouracil Topical Solution safe for nursing mother and child? Does Fluorouracil Topical Solution extracts into breast milk? Does Fluorouracil Topical Solution has any long term or short term side effects on infants? Can Fluorouracil Topical Solution influence milk supply or can Fluorouracil Topical Solution decrease milk supply in lactating mothers?

Fluorouracil Topical Solution lactation summary

Fluorouracil Topical Solution usage has low risk in breastfeeding
  • DrLact safety Score for Fluorouracil Topical Solution is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Fluorouracil Topical Solution may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Fluorouracil Topical Solution may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Fluorouracil Topical Solution low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Fluorouracil Topical Solution We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Fluorouracil Topical Solution usage in lactation

It has been locally used in the treatment of pre-cancer and cancer skin lesions. Topical absortion < 10% Avoid applying it on surfaces closed to the infant, or, cleanse it thoroughly. It’s not necessary to discontinue breastfeeding.

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Cisplatin(Unsafe)
Cyclophosphamide(Dangerous)
Doxorubicin(Dangerous)
Etoposide(Dangerous)
Hydroxyurea(Low Risk)
Mitoxantrone(Dangerous)
Vincristine(Dangerous)
Methotrexate(Low Risk)
Imatinib(Unsafe)
Trastuzumab(Unsafe)
Bevacizumab(Low Risk)
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Fluorouracil(Dangerous)
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Procarbazine(Dangerous)
Teniposide(Dangerous)
Thiotepa(Dangerous)
Tretinoin Oral(Dangerous)
Altretamine(Dangerous)
Anastrozole(Dangerous)
Arsenic-Trioxide(Dangerous)
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Bexarotene(Dangerous)
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.