Is Melphalan Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Melphalan? Is Melphalan safe for nursing mother and child? Does Melphalan extracts into breast milk? Does Melphalan has any long term or short term side effects on infants? Can Melphalan influence milk supply or can Melphalan decrease milk supply in lactating mothers?
Melphalan lactation summary
- DrLact safety Score for Melphalan is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Melphalan may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Melphalan may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Melphalan .
- Usage of Melphalan is in contradiction to breastfeeding hence if it is must to use Melphalan and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Melphalan usage in lactation
Drug is cleared from the body in 10 elimination half-lives. Return to breastfeeding is likely safe after 24 hours of pumping-discarding of the milk.
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