Question

I am a breastfeeding mother and i want to know if it is safe to use Pentostatin? Is Pentostatin safe for nursing mother and child? Does Pentostatin extracts into breast milk? Does Pentostatin has any long term or short term side effects on infants? Can Pentostatin influence milk supply or can Pentostatin decrease milk supply in lactating mothers?

Pentostatin lactation summary

Pentostatin is dangerous in breastfeeding
  • DrLact safety Score for Pentostatin is 7 out of 8 which is considered Dangerous as per our analyses.
  • A safety Score of 7 indicates that usage of Pentostatin may cause toxic or severe side effects in breastfed baby.
  • Our study of different scientific research indicates that Pentostatin may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Pentostatin .
  • Usage of Pentostatin is in contradiction to breastfeeding hence if it is must to use Pentostatin and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Pentostatin usage in lactation

Drug is cleared from the body in 8 elimination half-lives. Return to breastfeeding is likely safe after 2 days of pumping-discarding of the milk.

Alternate Drugs for Antineoplastic agents. ATC L01

Busulfan(Dangerous)
Cisplatin(Unsafe)
Cyclophosphamide(Dangerous)
Doxorubicin(Dangerous)
Etoposide(Dangerous)
Hydroxyurea(Low Risk)
Mitoxantrone(Dangerous)
Vincristine(Dangerous)
Methotrexate(Low Risk)
Imatinib(Unsafe)
Trastuzumab(Unsafe)
Bevacizumab(Low Risk)
Rituximab(Low Risk)
Alemtuzumab(Low Risk)
Fluorouracil(Dangerous)
Paclitaxel(Dangerous)
Carboplatin(Dangerous)
Cetuximab(Unsafe)
Ipilimumab(Unsafe)
Everolimus(Unsafe)
Thioguanine(Dangerous)
Dacarbazine(Dangerous)
Vinorelbine(Dangerous)
Bleomycin(Dangerous)
Vinblastine(Dangerous)
Nivolumab(Unsafe)
Nilotinib(Unsafe)
Dasatinib(Unsafe)
Cladribine(Dangerous)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Capecitabine(Dangerous)
Docetaxel(Dangerous)
Carmustine(Dangerous)
Exemestane(Dangerous)
Gemcitabine(Dangerous)
Dactinomycin(Dangerous)
Epirubucin(Dangerous)
Idarubicin-Hcl(Dangerous)
Ifosfamide(Dangerous)
Melphalan(Dangerous)
Mitomycin(Dangerous)
Oxaliplatin(Dangerous)
Procarbazine(Dangerous)
Teniposide(Dangerous)
Thiotepa(Dangerous)
Tretinoin Oral(Dangerous)
Altretamine(Dangerous)
Anastrozole(Dangerous)
Arsenic-Trioxide(Dangerous)
Asparaginase(Dangerous)
Bexarotene(Dangerous)
Cytarabine(Dangerous)
Chlorambucil(Dangerous)
Chlormethine(Dangerous)
Daunorubicin(Dangerous)
Rubidomycin(Dangerous)
Amethopterin(Low Risk)
Vlb(Dangerous)
Mechlorethamine(Dangerous)
5-ALA(Low Risk)
5-Fu(Dangerous)
MTX(Low Risk)
Daunomycin(Dangerous)
Actinomycin D(Dangerous)
Deoxycoformycin(Dangerous)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.