Is Auranofin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Auranofin? Is Auranofin safe for nursing mother and child? Does Auranofin extracts into breast milk? Does Auranofin has any long term or short term side effects on infants? Can Auranofin influence milk supply or can Auranofin decrease milk supply in lactating mothers?
Auranofin lactation summary
- DrLact safety Score for Auranofin is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Auranofin may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Auranofin may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Auranofin low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Auranofin We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Auranofin usage in lactation
We are working on a comment for this product.
Answer by DrLact: About Auranofin usage in lactation
Excretion of gold into milk after auranofen has not been studied. Case reports with other gold salts indicate that gold appears in milk in small quantities and at least a little of it is absorbed because it is detectable in the infant's urine. No convincing cases of toxicity have been reported. Opinions of authors of review articles vary from recommending avoidance to allowing use.[1][2][3][4][5] Monitoring for possible adverse effects in the breastfed infant would seem prudent.
Auranofin Side Effects in Breastfeeding
Four infants reportedly have been breastfed during maternal gold therapy (including gold sodium thiomalate and gold aurothioglucose).[6][7][8][9] Transient facial edema occurred in an 18-month-old infant, 3 months after the mother's treatment stopped.[6] The reaction was possibly due to gold in the mother's milk ingested by the infant.
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