Is Cytarabine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Cytarabine? Is Cytarabine safe for nursing mother and child? Does Cytarabine extracts into breast milk? Does Cytarabine has any long term or short term side effects on infants? Can Cytarabine influence milk supply or can Cytarabine decrease milk supply in lactating mothers?
Cytarabine lactation summary
- DrLact safety Score for Cytarabine is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Cytarabine may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Cytarabine may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Cytarabine .
- Usage of Cytarabine is in contradiction to breastfeeding hence if it is must to use Cytarabine and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Cytarabine usage in lactation
Drug is cleared from the body in 8 elimination half-lives. Resuming breastfeeding is likely safe after 24 hours of pumping-and-dumping.
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Cisplatin(Unsafe)
Cyclophosphamide(Dangerous)
Doxorubicin(Dangerous)
Etoposide(Dangerous)
Hydroxyurea(Low Risk)
Mercaptopurine(Safe)
Mitoxantrone(Dangerous)
Vincristine(Dangerous)
Methotrexate(Low Risk)
Imatinib(Unsafe)
Trastuzumab(Unsafe)
Bevacizumab(Low Risk)
Rituximab(Low Risk)
Alemtuzumab(Low Risk)
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Carboplatin(Dangerous)
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Brentuximab Vedotin(Low Risk)
Ipilimumab(Unsafe)
Everolimus(Unsafe)
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Dacarbazine(Dangerous)
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Pentostatin(Dangerous)
Procarbazine(Dangerous)
Teniposide(Dangerous)
Thiotepa(Dangerous)
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Imatinib Mesilate(Unsafe)
Altretamine(Dangerous)
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Bexarotene(Dangerous)
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