Is Daunorubicin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Daunorubicin? Is Daunorubicin safe for nursing mother and child? Does Daunorubicin extracts into breast milk? Does Daunorubicin has any long term or short term side effects on infants? Can Daunorubicin influence milk supply or can Daunorubicin decrease milk supply in lactating mothers?
Daunorubicin lactation summary
- DrLact safety Score for Daunorubicin is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Daunorubicin may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Daunorubicin may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Daunorubicin .
- Usage of Daunorubicin is in contradiction to breastfeeding hence if it is must to use Daunorubicin and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Daunorubicin usage in lactation
Drug is cleared from the body in 6 elimination half-lives. Resuming breastfeeding is likely safe after pumping-and-dumping for 10 days
Alternate Drugs for Antineoplastic agents. ATC L01
Busulfan(Dangerous)
Cisplatin(Unsafe)
Cyclophosphamide(Dangerous)
Doxorubicin(Dangerous)
Etoposide(Dangerous)
Hydroxyurea(Low Risk)
Mercaptopurine(Safe)
Mitoxantrone(Dangerous)
Vincristine(Dangerous)
Methotrexate(Low Risk)
Imatinib(Unsafe)
Trastuzumab(Unsafe)
Bevacizumab(Low Risk)
Rituximab(Low Risk)
Alemtuzumab(Low Risk)
Fluorouracil(Dangerous)
Paclitaxel(Dangerous)
Carboplatin(Dangerous)
Cetuximab(Unsafe)
Brentuximab Vedotin(Low Risk)
Ipilimumab(Unsafe)
Everolimus(Unsafe)
Thioguanine(Dangerous)
Dacarbazine(Dangerous)
Vinorelbine(Dangerous)
Bleomycin(Dangerous)
Vinblastine(Dangerous)
Nivolumab(Unsafe)
Nilotinib(Unsafe)
Dasatinib(Unsafe)
Cladribine(Dangerous)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Capecitabine(Dangerous)
Docetaxel(Dangerous)
Carmustine(Dangerous)
Exemestane(Dangerous)
Gemcitabine(Dangerous)
Dactinomycin(Dangerous)
Epirubucin(Dangerous)
Fluorouracil Topical Solution(Low Risk)
Idarubicin-Hcl(Dangerous)
Ifosfamide(Dangerous)
Melphalan(Dangerous)
Mitomycin(Dangerous)
Oxaliplatin(Dangerous)
Pentostatin(Dangerous)
Procarbazine(Dangerous)
Teniposide(Dangerous)
Thiotepa(Dangerous)
Tretinoin Oral(Dangerous)
Vinorelbine Tartrate(Dangerous)
Imatinib Mesilate(Unsafe)
Altretamine(Dangerous)
Aminoglutethimide(Dangerous)
5-Aminolevulinic Acid(Low Risk)
Hydroxycarbamide(Low Risk)
Anastrozole(Dangerous)
Arsenic-Trioxide(Dangerous)
Asparaginase(Dangerous)
Bexarotene(Dangerous)
Cytarabine(Dangerous)
Chlorambucil(Dangerous)
Chlormethine(Dangerous)
Rubidomycin(Dangerous)
Amethopterin(Low Risk)
Vincaleukoblastine(Dangerous)
Doxorubicin Hydrochloride(Dangerous)
Vlb(Dangerous)
Mechlorethamine(Dangerous)
Platinum Diamminodichloride(Unsafe)
4-Amino-10-methylfolic Acid(Low Risk)
5-ALA(Low Risk)
5-Fu(Dangerous)
6-Mercaptopurine(Safe)
6-Thiohypoxanthine(Safe)
6-Thioxopurine(Safe)
MTX(Low Risk)
Cytosine Arabinoside(Dangerous)
Daunomycin(Dangerous)
Actinomycin D(Dangerous)
Deoxycoformycin(Dangerous)