Is Trichloroacetaldehyde hydrate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Trichloroacetaldehyde hydrate? Is Trichloroacetaldehyde hydrate safe for nursing mother and child? Does Trichloroacetaldehyde hydrate extracts into breast milk? Does Trichloroacetaldehyde hydrate has any long term or short term side effects on infants? Can Trichloroacetaldehyde hydrate influence milk supply or can Trichloroacetaldehyde hydrate decrease milk supply in lactating mothers?
Trichloroacetaldehyde hydrate lactation summary
- DrLact safety Score for Trichloroacetaldehyde hydrate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Trichloroacetaldehyde hydrate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Trichloroacetaldehyde hydrate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Trichloroacetaldehyde hydrate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Trichloroacetaldehyde hydrate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Trichloroacetaldehyde hydrate usage in lactation
Sporadic use is harmless. (Used as a hypnotic drug for non painful procedures: CAT, EEG, MRI, etc. A repetitive use may be a cause of somnolence. Not commercially available in Spain as a sedative or hypnotic drug. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About Trichloroacetaldehyde hydrate usage in lactation
Short-term or occasional use of Trichloroacetaldehyde hydrate during breastfeeding is unlikely to adversely affect the breastfed infant, especially if the infant is older than 2 months. Because the active metabolite of Trichloroacetaldehyde hydrate has a long half-life, other sedative-hypnotics are preferred for long-term use during breastfeeding, especially while nursing a neonate or preterm infant. Monitor the infant for excessive drowsiness.
Trichloroacetaldehyde hydrate Side Effects in Breastfeeding
An old review article states that if an infant is breastfed within 45 minutes of a maternal dose of Trichloroacetaldehyde hydrate while she is taking 1.5 grams twice daily, the infant will fall into a prolonged, restless sleep.[3] A single maternal rectal dose of 1.3 grams Trichloroacetaldehyde hydrate in 50 women was stated to not adversely affect their breastfed newborn infants.[1] Minimal morning sedation occurred in a 5-month-old breastfed infant whose mother was taking 1.3 grams of dichloralphenazone (equivalent to about 1 gram of Trichloroacetaldehyde hydrate) every evening plus chlorpromazine 100 mg 3 times daily. The infant's overall development was said to be normal at 3 months of age.[2]
Alternate Drugs
Diazepam(Low Risk)
Secobarbital(Low Risk)
Clorazepate(Low Risk)
Alprazolam(Low Risk)
Propofol(Safe)
Chlordiazepoxide(Low Risk)
Sodium Oxybate(Low Risk)
Chloral Hydrate(Low Risk)
Nitrazepam(Low Risk)
Zolpidem(Safe)
Flunitrazepam(Unsafe)
Zaleplon(Safe)
Lormetazepam(Safe)
Triazolam(Low Risk)
Ketamine(Low Risk)
Temazepam(Low Risk)
Quazepam(Unsafe)
Estazolam(Low Risk)
Phenobarbital(Low Risk)
Flurazepam(Unsafe)
Oxazepam(Safe)
Meprobamate(Low Risk)
Midazolam(Safe)
Butalbital(Low Risk)
Lorazepam(Safe)
Butabarbital(Low Risk)
Eszopiclone(Low Risk)
Pentobarbital(Low Risk)