Is Mexiletine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Mexiletine? Is Mexiletine safe for nursing mother and child? Does Mexiletine extracts into breast milk? Does Mexiletine has any long term or short term side effects on infants? Can Mexiletine influence milk supply or can Mexiletine decrease milk supply in lactating mothers?
Mexiletine lactation summary
- DrLact safety Score for Mexiletine is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Mexiletine is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Mexiletine does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Mexiletine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Mexiletine usage in lactation
We are working on a comment for this product.
Answer by DrLact: About Mexiletine usage in lactation
Limited information indicates that maternal doses of mexiletine up to 600 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Because of the relative lack of data concerning breastfeeding during maternal mexiletine therapy, exclusively breastfed infants should be carefully monitored if this drug is used during lactation, possibly including measurement of serum levels to rule out toxicity if there is a concern.
Mexiletine Side Effects in Breastfeeding
Failure to thrive in a 17-day-old breastfed infant may possibly have been caused by maternal use of mexiletine or atenolol (or both). The authors felt that mexiletine was unlikely to have caused the problem.[3]
Alternate Drugs
Bisoprolol(Low Risk)
Atenolol(Unsafe)
Acebutolol(Unsafe)
Verapamil(Safe)
Lidocaine(Safe)
Quinidine(Safe)
Timolol(Safe)
Propafenone(Low Risk)
Sotalol(Low Risk)
Procainamide(Safe)
Propranolol(Safe)
Mexiletine(Safe)
Flecainide(Safe)
Disopyramide(Safe)
Diltiazem(Safe)
Nadolol(Unsafe)
Digoxin(Safe)
Metoprolol(Safe)
Amiodarone(Unsafe)
Levobunolol(Low Risk)
Labetalol(Safe)