Question

I am a breastfeeding mother and i want to know if it is safe to use Dichloralantipyrin? Is Dichloralantipyrin safe for nursing mother and child? Does Dichloralantipyrin extracts into breast milk? Does Dichloralantipyrin has any long term or short term side effects on infants? Can Dichloralantipyrin influence milk supply or can Dichloralantipyrin decrease milk supply in lactating mothers?

Answer by DrLact: About Dichloralantipyrin usage in lactation

Short-term or occasional use of Dichloralantipyrin during breastfeeding is unlikely to adversely affect the breastfed infant, especially if the infant is older than 2 months. Because the active metabolite, trichloroethanol, has a long half-life, long-term use of repeated doses during breastfeeding could result in infant sedation, especially while nursing a neonate or preterm infant. The low doses of Dichloralantipyrin found in combination migraine products (e.g., Midrin) are less likely to cause drowsiness in the infant unless doses are repeated several times daily. The antipyrine component of Dichloralantipyrin is considered unlikely to harm the infant.[1][2] Monitor the infant for excessive drowsiness during use.

Dichloralantipyrin Side Effects in Breastfeeding

Minimal morning sedation occurred in a 5-month-old breastfed infant whose mother was taking 1.3 grams of Dichloralantipyrin (equivalent to about 1 gram of chloral hydrate) every evening plus chlorpromazine 100 mg 3 times daily. The infant's overall development was said to be normal at 3 months of age.[3]

Alternate Drugs

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