Question

I am a breastfeeding mother and i want to know if it is safe to use Dichloralantipyrine? Is Dichloralantipyrine safe for nursing mother and child? Does Dichloralantipyrine extracts into breast milk? Does Dichloralantipyrine has any long term or short term side effects on infants? Can Dichloralantipyrine influence milk supply or can Dichloralantipyrine decrease milk supply in lactating mothers?

Answer by DrLact: About Dichloralantipyrine usage in lactation

Short-term or occasional use of Dichloralantipyrine during breastfeeding is unlikely to adversely affect the breastfed infant, especially if the infant is older than 2 months. Because the active metabolite, trichloroethanol, has a long half-life, long-term use of repeated doses during breastfeeding could result in infant sedation, especially while nursing a neonate or preterm infant. The low doses of Dichloralantipyrine found in combination migraine products (e.g., Midrin) are less likely to cause drowsiness in the infant unless doses are repeated several times daily. The antipyrine component of Dichloralantipyrine is considered unlikely to harm the infant.[1][2] Monitor the infant for excessive drowsiness during use.

Dichloralantipyrine Side Effects in Breastfeeding

Minimal morning sedation occurred in a 5-month-old breastfed infant whose mother was taking 1.3 grams of Dichloralantipyrine (equivalent to about 1 gram of chloral hydrate) every evening plus chlorpromazine 100 mg 3 times daily. The infant's overall development was said to be normal at 3 months of age.[3]

Alternate Drugs

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