Is Levosulpiride Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Levosulpiride? Is Levosulpiride safe for nursing mother and child? Does Levosulpiride extracts into breast milk? Does Levosulpiride has any long term or short term side effects on infants? Can Levosulpiride influence milk supply or can Levosulpiride decrease milk supply in lactating mothers?
Levosulpiride lactation summary
- DrLact safety Score for Levosulpiride is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Levosulpiride is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Levosulpiride does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Levosulpiride safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Levosulpiride usage in lactation
IL-enantiomer of Sulpiride. Both share similar characteristics and properties. More frequently used as anti-emetic and prokinetic than as anti-psychotic agent. Sulpiride is a Dopamine-selective antagonist that increases Prolactin serum levels which is used as anti-psychotic, anti-depressant, anti-emetic and prokinetic agent. Its property as galactogogue has been questioned because poor methodology used by published studies that intended to prove it. Doses at 50 mg twice-a-day after early post-partum for four weeks have been used to stimulate initiation of lactation without adverse effects in the mother. Excretion into breast milk is moderate, however, side-effects in breastfed infants from treated mothers were not observed. Best galactagogue effect is attained by promoting frequent breastfeeding on-demand along with the use of a proper lactation technique. Effective support to breastfeeding mothers, woman empowerment related to her ability to breastfeed and self-confidence are important factors to reinforce before start using galactagogue drugs.