Question

I am a breastfeeding mother and i want to know if it is safe to use 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid? Is 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid safe for nursing mother and child? Does 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid extracts into breast milk? Does 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid has any long term or short term side effects on infants? Can 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid influence milk supply or can 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid decrease milk supply in lactating mothers?

Answer by DrLact: About 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid usage in lactation

Amounts of 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid in milk are very small. Existing data indicate that no waiting period is required before resuming breastfeeding after 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid anesthesia. Breastfeeding can be resumed as soon as the mother has recovered sufficiently from general anesthesia to nurse.[1][2] When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure.

5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid Possible Effects in Breastfeeding

A randomized, but nonblinded, study in women undergoing cesarean section compared epidural anesthesia with bupivacaine to general anesthesia with intravenous 5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid 4 mg/kg and succinylcholine 1.5 mg/kg for induction followed by nitrous oxide and isoflurane. The time to the first breastfeed was significantly shorter (107 vs 228 minutes) with the epidural anesthesia than with general anesthesia. This difference was probably caused by the anesthesia's effects on the infant, because the Apgar and neurologic and adaptive scores were significantly lower in the general anesthesia group of infants.[6]

Alternate Drugs

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.