Is Intraval Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Intraval? Is Intraval safe for nursing mother and child? Does Intraval extracts into breast milk? Does Intraval has any long term or short term side effects on infants? Can Intraval influence milk supply or can Intraval decrease milk supply in lactating mothers?

Amounts of Intraval in milk are very small. Existing data indicate that no waiting period is required before resuming breastfeeding after Intraval anesthesia. Breastfeeding can be resumed as soon as the mother has recovered sufficiently from general anesthesia to nurse.[1][2] When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure.

A randomized, but nonblinded, study in women undergoing cesarean section compared epidural anesthesia with bupivacaine to general anesthesia with intravenous Intraval 4 mg/kg and succinylcholine 1.5 mg/kg for induction followed by nitrous oxide and isoflurane. The time to the first breastfeed was significantly shorter (107 vs 228 minutes) with the epidural anesthesia than with general anesthesia. This difference was probably caused by the anesthesia's effects on the infant, because the Apgar and neurologic and adaptive scores were significantly lower in the general anesthesia group of infants.[6]