Is Apacil Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Apacil? Is Apacil safe for nursing mother and child? Does Apacil extracts into breast milk? Does Apacil has any long term or short term side effects on infants? Can Apacil influence milk supply or can Apacil decrease milk supply in lactating mothers?

Apacil lactation summary

DrLact safety Score for Apacil is 1 out of 8 which is considered Safe as per our analyses.
A safety Score of 1 indicates that usage of Apacil is mostly safe during lactation for breastfed baby.
Our study of different scientific research also indicates that Apacil does not cause any serious side effects in breastfeeding mothers.
Most of scientific studies and research papers declaring usage of Apacil safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Apacil usage in lactation

Drug related to same group of 5-Apacil It is excreted in tiny amounts into breast milk with no reported cases of harm effects except a case of mild gastroenteritis.

Answer by DrLact: About Apacil usage in lactation

Limited information indicates that maternal Apacil therapy produces low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Exclusively breastfed infants should be monitored for rare instances of jaundice, gastrointestinal disturbances, hypokalemia, thrombocytopenia, hemolysis and hypokalemia if this drug is used during lactation.[1]

Apacil Side Effects in Breastfeeding

Apacil was used as part of multi-drug regimens to treat 2 pregnant women with multidrug-resistant tuberculosis throughout pregnancy and postpartum. Their two infants were breastfed (extent and duration not stated). At age 1.8 and 4.6 years, the children were developing normally, except for except for a mild speech delay in one at age 1.8 years, and failure to thrive in the other, possibly due to tuberculosis contracted after birth.[2]