Is Doxazosin Mesylate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Doxazosin Mesylate? Is Doxazosin Mesylate safe for nursing mother and child? Does Doxazosin Mesylate extracts into breast milk? Does Doxazosin Mesylate has any long term or short term side effects on infants? Can Doxazosin Mesylate influence milk supply or can Doxazosin Mesylate decrease milk supply in lactating mothers?
Doxazosin Mesylate lactation summary
- DrLact safety Score for Doxazosin Mesylate is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Doxazosin Mesylate is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Doxazosin Mesylate does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Doxazosin Mesylate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Doxazosin Mesylate usage in lactation
It is excreted into breast milk in clinically non-significant amount possibly due to its high plasma protein binding capacity. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug may be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About Doxazosin Mesylate usage in lactation
Limited information indicates that maternal doses of 4 mg daily produce low very levels in milk and would not be expected to cause any adverse effects in breastfed infants.
Doxazosin Mesylate Possible Effects in Breastfeeding
Relevant published information in nursing mothers was not found as of the revision date. However, the pharmacologically similar drug prazosin does not affect serum prolactin concentration in patients with hypertension,[3][4] indicating that doxazosin may not affect prolactin levels. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs for Anti-hypertensive Anti Alpha-adrenergics, Vasodilators & other. ATC C02
Hydralazine(Safe)
Methyldopa(Safe)
Minoxidil(Safe)
Reserpine(Unsafe)
Guanfacine(Low Risk)
Doxazosin(Safe)
Prazosin(Unsafe)
Terazosin(Unsafe)
Bosentan(Low Risk)
Clonidine-Hcl(Low Risk)
Diazoxide(Unsafe)
Moxonidine(Unsafe)
Nitroprussiate(Unsafe)
Urapidil-Hcl(Unsafe)