Question

I am a breastfeeding mother and i want to know if it is safe to use 5-21-05-00415 (Beilstein Handbook Reference)? Is 5-21-05-00415 (Beilstein Handbook Reference) safe for nursing mother and child? Does 5-21-05-00415 (Beilstein Handbook Reference) extracts into breast milk? Does 5-21-05-00415 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 5-21-05-00415 (Beilstein Handbook Reference) influence milk supply or can 5-21-05-00415 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

5-21-05-00415 (Beilstein Handbook Reference) lactation summary

5-21-05-00415 (Beilstein Handbook Reference) is safe in breastfeeding
  • DrLact safety Score for 5-21-05-00415 (Beilstein Handbook Reference) is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 5-21-05-00415 (Beilstein Handbook Reference) is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 5-21-05-00415 (Beilstein Handbook Reference) does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 5-21-05-00415 (Beilstein Handbook Reference) safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-21-05-00415 (Beilstein Handbook Reference) usage in lactation

A laxative which acts as stimulant in the intestine. A low oral bioavailability due to minimal intestinal absorption that renders the plasma levels being very low would explain the non passage to breast milk observed (undetectable levels: Friedrich 2011). On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.

Answer by DrLact: About 5-21-05-00415 (Beilstein Handbook Reference) usage in lactation

5-21-05-00415 (Beilstein Handbook Reference) is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. 5-21-05-00415 (Beilstein Handbook Reference) can be taken during breastfeeding and no special precautions are required.
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