Is Bis(p-acetoxyphenyl)-2-pyridylmethane Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Bis(p-acetoxyphenyl)-2-pyridylmethane? Is Bis(p-acetoxyphenyl)-2-pyridylmethane safe for nursing mother and child? Does Bis(p-acetoxyphenyl)-2-pyridylmethane extracts into breast milk? Does Bis(p-acetoxyphenyl)-2-pyridylmethane has any long term or short term side effects on infants? Can Bis(p-acetoxyphenyl)-2-pyridylmethane influence milk supply or can Bis(p-acetoxyphenyl)-2-pyridylmethane decrease milk supply in lactating mothers?
Bis(p-acetoxyphenyl)-2-pyridylmethane lactation summary
- DrLact safety Score for Bis(p-acetoxyphenyl)-2-pyridylmethane is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Bis(p-acetoxyphenyl)-2-pyridylmethane is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Bis(p-acetoxyphenyl)-2-pyridylmethane does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Bis(p-acetoxyphenyl)-2-pyridylmethane safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Bis(p-acetoxyphenyl)-2-pyridylmethane usage in lactation
A laxative which acts as stimulant in the intestine. A low oral bioavailability due to minimal intestinal absorption that renders the plasma levels being very low would explain the non passage to breast milk observed (undetectable levels: Friedrich 2011). On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.
Answer by DrLact: About Bis(p-acetoxyphenyl)-2-pyridylmethane usage in lactation
Bis(p-acetoxyphenyl)-2-pyridylmethane is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. Bis(p-acetoxyphenyl)-2-pyridylmethane can be taken during breastfeeding and no special precautions are required.
Alternate Drugs
Magnesium Sulfate(Safe)
Magnesium Oxide(Safe)
Magnesium Hydroxide(Safe)
Sodium Picosulfate(Safe)
Cascara Sagrada(Low Risk)
Castor(Unsafe)
Bisacodyl(Safe)
Senna(Safe)
Metoclopramide(Safe)
Octreotide(Safe)
Mesalamine(Safe)
Doxylamine(Unsafe)
Magnesium Sulfate(Safe)
Loperamide(Safe)
Magnesium Oxide(Safe)
Certolizumab Pegol(Safe)
Rabeprazole(Safe)
Magnesium Hydroxide(Safe)
Droperidol(Low Risk)
Pantoprazole(Safe)
Dexlansoprazole(Safe)
Lansoprazole(Safe)
Infliximab(Safe)
Cisapride(Safe)
Esomeprazole(Safe)
Sodium Picosulfate(Safe)
Docusate(Safe)
Ranitidine(Safe)
Misoprostol(Safe)
Omeprazole(Safe)
Adalimumab(Safe)
Nizatidine(Safe)
Cascara Sagrada(Low Risk)
Domperidone(Safe)
Famotidine(Safe)
Rifaximin(Safe)
Alosetron(Low Risk)
Ursodiol(Safe)
Cimetidine(Low Risk)
Trimethobenzamide(Unsafe)
Sucralfate(Safe)
Thiethylperazine(Unsafe)
Bisacodyl(Safe)
Senna(Safe)
Prochlorperazine(Unsafe)
Etanercept(Safe)
Dimenhydrinate(Low Risk)
Peppermint(Safe)
Sulfasalazine(Safe)
Linaclotide(Safe)
Cyclizine(Low Risk)
Olsalazine(Safe)