Is Di-(p-acetoxyphenyl)-2-pyridylmethane Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Di-(p-acetoxyphenyl)-2-pyridylmethane? Is Di-(p-acetoxyphenyl)-2-pyridylmethane safe for nursing mother and child? Does Di-(p-acetoxyphenyl)-2-pyridylmethane extracts into breast milk? Does Di-(p-acetoxyphenyl)-2-pyridylmethane has any long term or short term side effects on infants? Can Di-(p-acetoxyphenyl)-2-pyridylmethane influence milk supply or can Di-(p-acetoxyphenyl)-2-pyridylmethane decrease milk supply in lactating mothers?
Di-(p-acetoxyphenyl)-2-pyridylmethane lactation summary
- DrLact safety Score for Di-(p-acetoxyphenyl)-2-pyridylmethane is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Di-(p-acetoxyphenyl)-2-pyridylmethane is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Di-(p-acetoxyphenyl)-2-pyridylmethane does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Di-(p-acetoxyphenyl)-2-pyridylmethane safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Di-(p-acetoxyphenyl)-2-pyridylmethane usage in lactation
A laxative which acts as stimulant in the intestine. A low oral bioavailability due to minimal intestinal absorption that renders the plasma levels being very low would explain the non passage to breast milk observed (undetectable levels: Friedrich 2011). On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.
Answer by DrLact: About Di-(p-acetoxyphenyl)-2-pyridylmethane usage in lactation
Di-(p-acetoxyphenyl)-2-pyridylmethane is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. Di-(p-acetoxyphenyl)-2-pyridylmethane can be taken during breastfeeding and no special precautions are required.
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