Question

I am a breastfeeding mother and i want to know if it is safe to use Di-(p-acetoxyphenyl)-2-pyridylmethane? Is Di-(p-acetoxyphenyl)-2-pyridylmethane safe for nursing mother and child? Does Di-(p-acetoxyphenyl)-2-pyridylmethane extracts into breast milk? Does Di-(p-acetoxyphenyl)-2-pyridylmethane has any long term or short term side effects on infants? Can Di-(p-acetoxyphenyl)-2-pyridylmethane influence milk supply or can Di-(p-acetoxyphenyl)-2-pyridylmethane decrease milk supply in lactating mothers?

Di-(p-acetoxyphenyl)-2-pyridylmethane lactation summary

Di-(p-acetoxyphenyl)-2-pyridylmethane is safe in breastfeeding
  • DrLact safety Score for Di-(p-acetoxyphenyl)-2-pyridylmethane is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Di-(p-acetoxyphenyl)-2-pyridylmethane is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Di-(p-acetoxyphenyl)-2-pyridylmethane does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Di-(p-acetoxyphenyl)-2-pyridylmethane safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Di-(p-acetoxyphenyl)-2-pyridylmethane usage in lactation

A laxative which acts as stimulant in the intestine. A low oral bioavailability due to minimal intestinal absorption that renders the plasma levels being very low would explain the non passage to breast milk observed (undetectable levels: Friedrich 2011). On prevention or treating constipation, it is essential a balanced and rich-in-fiber diet along with a lot of fluids and physical exercise.

Answer by DrLact: About Di-(p-acetoxyphenyl)-2-pyridylmethane usage in lactation

Di-(p-acetoxyphenyl)-2-pyridylmethane is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. Di-(p-acetoxyphenyl)-2-pyridylmethane can be taken during breastfeeding and no special precautions are required.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.