Is UNII-DL2R53P963 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-DL2R53P963? Is UNII-DL2R53P963 safe for nursing mother and child? Does UNII-DL2R53P963 extracts into breast milk? Does UNII-DL2R53P963 has any long term or short term side effects on infants? Can UNII-DL2R53P963 influence milk supply or can UNII-DL2R53P963 decrease milk supply in lactating mothers?
UNII-DL2R53P963 lactation summary
- DrLact safety Score for UNII-DL2R53P963 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-DL2R53P963 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-DL2R53P963 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-DL2R53P963 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-DL2R53P963 usage in lactation
Pharmacokinetic data (high volume of distribution and molecular weight) would explain the minimal excretion into breast milk mentioned in two older reports. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption.
Answer by DrLact: About UNII-DL2R53P963 usage in lactation
Limited data indicate that colistin is minimally excreted into breastmilk following intramuscular administration of UNII-DL2R53P963. Because colistin is poorly absorbed orally, it is unlikely to be absorbed in appreciable amounts by the infant or adversely affect the breastfed infant. However, no studies have evaluated serum levels or adverse effects in breastfed infants whose mothers were receiving UNII-DL2R53P963. Breastfeeding is acceptable with the use of inhaled colistin or UNII-DL2R53P963.
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