Question

I am a breastfeeding mother and i want to know if it is safe to use 5-22-02-00487 (Beilstein Handbook Reference)? Is 5-22-02-00487 (Beilstein Handbook Reference) safe for nursing mother and child? Does 5-22-02-00487 (Beilstein Handbook Reference) extracts into breast milk? Does 5-22-02-00487 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 5-22-02-00487 (Beilstein Handbook Reference) influence milk supply or can 5-22-02-00487 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

Answer by DrLact: About 5-22-02-00487 (Beilstein Handbook Reference) usage in lactation

No data exist on the use of 5-22-02-00487 (Beilstein Handbook Reference) during breastfeeding. One expert panel considers 5-22-02-00487 (Beilstein Handbook Reference) to be unacceptable during breastfeeding.[1] Based on its chemical and pharmacological similarity to narcotics, occasional small doses of 5-22-02-00487 (Beilstein Handbook Reference) may be acceptable while breastfeeding an older infant, but alternatives are preferred, especially while nursing a newborn.

Alternate Drugs

Loperamide(Safe)
Diphenoxylate
Loperamide(Safe)
Alosetron(Low Risk)
Cyproheptadine
Psyllium
Buckthorn
Trimethobenzamide(Unsafe)
Metoclopramide(Safe)
Peppermint(Safe)
Rabeprazole(Safe)
Plecanatide
Magnesium Sulfate(Safe)
Cyclizine(Low Risk)
Pantoprazole(Safe)
Lubiprostone
Magnesium Hydroxide(Safe)
Octreotide(Safe)
Lansoprazole(Safe)
Infliximab(Safe)
Propantheline
Esomeprazole(Safe)
Linaclotide(Safe)
Docusate(Safe)
Certolizumab Pegol(Safe)
Famotidine(Safe)
Droperidol(Low Risk)
Diphenoxylate
Dexlansoprazole(Safe)
Vedolizumab
Cimetidine(Low Risk)
Cisapride(Safe)
Doxylamine(Unsafe)
Cascara Sagrada(Low Risk)
Balsalazide
Ranitidine(Safe)
Magnesium Oxide(Safe)
Bismuth Subsalicylate
Misoprostol(Safe)
Magnesium Citrate
Bisacodyl(Safe)
Adalimumab(Safe)
Sodium Picosulfate(Safe)
Antacids
Thiethylperazine(Unsafe)
Domperidone(Safe)
Sodium Phosphate
Sulfasalazine(Safe)
Prochlorperazine(Unsafe)
Ursodiol(Safe)
Omeprazole(Safe)
Olsalazine(Safe)
Etanercept(Safe)
Sucralfate(Safe)
Nizatidine(Safe)
Rifaximin(Safe)
Mesalamine(Safe)
Dimenhydrinate(Low Risk)
Senna(Safe)
Mineral Oil
Morphine(Low Risk)
Methadone(Safe)
Meperidine(Low Risk)
Hydromorphone
Piritramide
Hydrocodone(Low Risk)
Fentanyl(Safe)
Tramadol(Safe)
Heroin(Dangerous)
Diphenoxylate
Sufentanil(Low Risk)
Dihydrocodeine(Low Risk)
Codeine(Unsafe)
Remifentanil(Low Risk)
Butorphanol(Low Risk)
Buprenorphine(Safe)
Propoxyphene(Safe)
Alfentanil(Safe)
Pentazocine(Low Risk)
Oxycodone(Unsafe)
Nalbuphine

Synonyms of 5-22-02-00487 (Beilstein Handbook Reference)

R-1132
BRN 0503374
1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester
1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid ethyl ester
Difenossilato [DCIT]
Difenoxilato [INN-Spanish]
Difenoxilato [Spanish]
Diphenoxylatum [INN-Latin]
Diphenoxylatum [Latin]
2,2-Diphenyl-4-(4-carbethoxy-4-phenylpiperidino)butyronitrile
EINECS 213-020-1
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylate
HSDB 3067
Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester
Difenossilato
Difenoxilato
Diphenoxylatum
NIH 7562
UNII-73312P173G
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.