Question

I am a breastfeeding mother and i want to know if it is safe to use Dioctyl sulfosuccinic acid? Is Dioctyl sulfosuccinic acid safe for nursing mother and child? Does Dioctyl sulfosuccinic acid extracts into breast milk? Does Dioctyl sulfosuccinic acid has any long term or short term side effects on infants? Can Dioctyl sulfosuccinic acid influence milk supply or can Dioctyl sulfosuccinic acid decrease milk supply in lactating mothers?

Dioctyl sulfosuccinic acid lactation summary

Dioctyl sulfosuccinic acid is safe in breastfeeding
  • DrLact safety Score for Dioctyl sulfosuccinic acid is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Dioctyl sulfosuccinic acid is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Dioctyl sulfosuccinic acid does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Dioctyl sulfosuccinic acid safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dioctyl sulfosuccinic acid usage in lactation

Anionic surfactant that acts as an emollient laxative. It is also used to treat the retention of ear cerumen. It is minimally absorbed in the duodenum-jejunum and excreted in the bile. No problems have been observed in infants whose mothers were treated, except one case of diarrhea that was possibly due to other laxative medication took by the mother (Greenhalf 1973). The Institute at the American Gastroenterological Association (AGA) consideres it to be compatible while breastfeeding (Mahadevan 2006).

Answer by DrLact: About Dioctyl sulfosuccinic acid usage in lactation

Dioctyl sulfosuccinic acid is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[2]

Dioctyl sulfosuccinic acid Side Effects in Breastfeeding

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing Dioctyl sulfosuccinic acid in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[1] The diarrhea was most likely caused by the danthron.
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