Question

I am a breastfeeding mother and i want to know if it is safe to use Streptodornase? Is Streptodornase safe for nursing mother and child? Does Streptodornase extracts into breast milk? Does Streptodornase has any long term or short term side effects on infants? Can Streptodornase influence milk supply or can Streptodornase decrease milk supply in lactating mothers?

Streptodornase lactation summary

Streptodornase is safe in breastfeeding
  • DrLact safety Score for Streptodornase is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Streptodornase is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Streptodornase does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Streptodornase safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Streptodornase usage in lactation

Fibrinolytic enzyme obtained from hemolytic streptococcus strains. It is used topically with streptokinase to remove clots or purulent material from wounds or cavities (pleura, bladder). There is no scientific support for the effectiveness of its oral administration, since there is evidence of its lack of oral absorption and absence of fibrinolytic properties when taken orally (Oliven 1981, Vonmoos 1979). Since the last update we have not found published data on its excretion in breast milk, but given the lack of absorption when taken orally it is unlikely to be excreted in breast milk in significant amounts which furthermore would not be absorbed in the infant’s intestine.

Alternate Drugs for Antithrombotics: Enzymes. ATC B01AD

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