Is Streptokinase Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Streptokinase? Is Streptokinase safe for nursing mother and child? Does Streptokinase extracts into breast milk? Does Streptokinase has any long term or short term side effects on infants? Can Streptokinase influence milk supply or can Streptokinase decrease milk supply in lactating mothers?
Streptokinase lactation summary
- DrLact safety Score for Streptokinase is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Streptokinase is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Streptokinase does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Streptokinase safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Streptokinase usage in lactation
A fibrinolytic enzyme obtained from the culture of streptococcus strains. Administered intravenously to treat acute myocardial infarction, pulmonary embolism and deep-vein thrombosis. It is also used topically with streptokinase to remove clots or purulent matter from wounds or cavities (pleura, bladder). There is no scientific support for the effectiveness of its oral administration, since there is evidence of its lack of oral absorption and absence of fibrinolytic properties when taken orally (Oliven 1981, Vonmoos 1979). Since the last update we have not found published data on its excretion in breast milk, but given the lack of absorption when taken orally, high molecular weight and very rapid elimination when administered intravenously, it is unlikely to be excreted in breast milk in significant quantities which furthermore would not be absorbed in the infant's intestine.