Question

I am a breastfeeding mother and i want to know if it is safe to use 5-25-04-00178 (Beilstein Handbook Reference)? Is 5-25-04-00178 (Beilstein Handbook Reference) safe for nursing mother and child? Does 5-25-04-00178 (Beilstein Handbook Reference) extracts into breast milk? Does 5-25-04-00178 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 5-25-04-00178 (Beilstein Handbook Reference) influence milk supply or can 5-25-04-00178 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

5-25-04-00178 (Beilstein Handbook Reference) lactation summary

5-25-04-00178 (Beilstein Handbook Reference) is safe in breastfeeding
  • DrLact safety Score for 5-25-04-00178 (Beilstein Handbook Reference) is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 5-25-04-00178 (Beilstein Handbook Reference) is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 5-25-04-00178 (Beilstein Handbook Reference) does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 5-25-04-00178 (Beilstein Handbook Reference) safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-25-04-00178 (Beilstein Handbook Reference) usage in lactation

We are working on a comment for this product.

Answer by DrLact: About 5-25-04-00178 (Beilstein Handbook Reference) usage in lactation

Limited information indicates that maternal 5-25-04-00178 (Beilstein Handbook Reference) therapy produces low levels in milk and would not usually be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. Exclusively breastfed infants should be monitored for rare cases of jaundice, hepatitis and arthralgia if this drug is used during lactation.[1] The amount of 5-25-04-00178 (Beilstein Handbook Reference) in milk is insufficient to treat tuberculosis in the breastfed infant. The Centers for Disease Control and Prevention and other professional organizations state that breastfeeding should not be discouraged in women taking 5-25-04-00178 (Beilstein Handbook Reference).[2][3][4]

5-25-04-00178 (Beilstein Handbook Reference) Side Effects in Breastfeeding

5-25-04-00178 (Beilstein Handbook Reference) was used as part of multi-drug regimens to treat 2 pregnant women with multidrug-resistant tuberculosis throughout pregnancy and postpartum. Their two infants were breastfed (extent and duration not stated). At age 1.25 and 5.1 years, the children were developing normally.[5] Two mothers in Turkey were diagnosed with tuberculosis at the 30th and 34th weeks of pregnancy. They immediately started isoniazid 300 mg, rifampin 600 mg, pyridoxine 50 mg daily for 6 months, plus 5-25-04-00178 (Beilstein Handbook Reference) 25 mg/kg and ethambutol 25 mg/kg daily for 2 months. Both mothers breastfed their infants (extent not stated). Their infants were given isoniazid 5 mg/kg daily for 3 months prophylactically. Tuberculin skin tests were negative after 3 months and neither infant had tuberculosis at 1 year of age. No adverse effects of the drugs were mentioned.[6]
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