Question

I am a breastfeeding mother and i want to know if it is safe to use Nifedipine? Is Nifedipine safe for nursing mother and child? Does Nifedipine extracts into breast milk? Does Nifedipine has any long term or short term side effects on infants? Can Nifedipine influence milk supply or can Nifedipine decrease milk supply in lactating mothers?

Nifedipine lactation summary

Nifedipine is safe in breastfeeding
  • DrLact safety Score for Nifedipine is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Nifedipine is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Nifedipine does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Nifedipine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Nifedipine usage in lactation

Excreted into breast milk in non-significant amount with no problems among breastfed infants whose mothers were treated with this medication. No alteration on breast milk composition has been seen. Shown to be effective at a dose of 10 - 20 mg three times-a-day for pain relief related to Raynaud's phenomena of the nipple, which is a highly painful vasospasm triggered by cold exposition or trauma produced by inadequate latch-on to the breast. Side effect on the mother should be addressed. American Academy of Pediatrics 2001: Maternal Medication Usually Compatible With Breastfeeding. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About Nifedipine usage in lactation

Because of the low levels of nifedipine in breastmilk, amounts ingested by the infant are small and no adverse effects have been reported among a limited number of infants exposed to nifedipine in breastmilk. Nifedipine is used to treat painful nipple vasospasm (e.g., Raynaud phenomenon) in nursing mothers.[1]

Nifedipine Side Effects in Breastfeeding

No adverse reactions have been reported among infants exposed to nifedipine in breastmilk mostly at maternal dosages of 30 mg daily beginning shortly postpartum and continuing for up to 6 months in some.[2][5][6][7][8][9][10][11]

Nifedipine Possible Effects in Breastfeeding

No direct effects are known. However, nifedipine has been used to decrease the pain of nipple vasospasm (or Raynaud phenomenon of the nipple), allowing mothers to continue nursing who might otherwise discontinue breastfeeding. The dosage of nifedipine reportedly used to treat the condition is 30 to 60 mg daily either as a single dose of a sustained-release product or 10 to 20 mg 3 times daily of an immediate-release product. Lower dosages can be tried if these doses are not tolerated.[1][6][7][8][9][12] Nifedipine had no effect on milk composition (sodium, potassium, calcium, chloride, nitrogen, phosphorus and total lipids) in one woman.[3]

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Felodipine(Low Risk)
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Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.