Is 5-Allyl-5-(1-methylbutyl)malonylurea Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 5-Allyl-5-(1-methylbutyl)malonylurea? Is 5-Allyl-5-(1-methylbutyl)malonylurea safe for nursing mother and child? Does 5-Allyl-5-(1-methylbutyl)malonylurea extracts into breast milk? Does 5-Allyl-5-(1-methylbutyl)malonylurea has any long term or short term side effects on infants? Can 5-Allyl-5-(1-methylbutyl)malonylurea influence milk supply or can 5-Allyl-5-(1-methylbutyl)malonylurea decrease milk supply in lactating mothers?
5-Allyl-5-(1-methylbutyl)malonylurea lactation summary
- DrLact safety Score for 5-Allyl-5-(1-methylbutyl)malonylurea is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 5-Allyl-5-(1-methylbutyl)malonylurea may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 5-Allyl-5-(1-methylbutyl)malonylurea may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 5-Allyl-5-(1-methylbutyl)malonylurea low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 5-Allyl-5-(1-methylbutyl)malonylurea We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 5-Allyl-5-(1-methylbutyl)malonylurea usage in lactation
Avoid nursing within the next 3 hours after having taken this drug. Not commercially available in Spain.
Answer by DrLact: About 5-Allyl-5-(1-methylbutyl)malonylurea usage in lactation
Because there is little published experience with 5-Allyl-5-(1-methylbutyl)malonylurea during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
5-Allyl-5-(1-methylbutyl)malonylurea Possible Effects in Breastfeeding
5-Allyl-5-(1-methylbutyl)malonylurea 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced 5-Allyl-5-(1-methylbutyl)malonylurea 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced substantially.[2] In one small study, women given promethazine with meperidine and 5-Allyl-5-(1-methylbutyl)malonylurea during labor, had the time to lactogenesis II prolonged by 14 hours. Women given meperidine or 5-Allyl-5-(1-methylbutyl)malonylurea without promethazine had lactogenesis II prolonged 7 hours compared to unmedicated women, but the difference was not statistically significant.[3]
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