Is HSDB 3182 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use HSDB 3182? Is HSDB 3182 safe for nursing mother and child? Does HSDB 3182 extracts into breast milk? Does HSDB 3182 has any long term or short term side effects on infants? Can HSDB 3182 influence milk supply or can HSDB 3182 decrease milk supply in lactating mothers?
HSDB 3182 lactation summary
- DrLact safety Score for HSDB 3182 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of HSDB 3182 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that HSDB 3182 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of HSDB 3182 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using HSDB 3182 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About HSDB 3182 usage in lactation
Avoid nursing within the next 3 hours after having taken this drug. Not commercially available in Spain.
Answer by DrLact: About HSDB 3182 usage in lactation
Because there is little published experience with HSDB 3182 during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
HSDB 3182 Possible Effects in Breastfeeding
HSDB 3182 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced HSDB 3182 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced substantially.[2] In one small study, women given promethazine with meperidine and HSDB 3182 during labor, had the time to lactogenesis II prolonged by 14 hours. Women given meperidine or HSDB 3182 without promethazine had lactogenesis II prolonged 7 hours compared to unmedicated women, but the difference was not statistically significant.[3]
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