Is Pramil Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pramil? Is Pramil safe for nursing mother and child? Does Pramil extracts into breast milk? Does Pramil has any long term or short term side effects on infants? Can Pramil influence milk supply or can Pramil decrease milk supply in lactating mothers?
Pramil lactation summary
- DrLact safety Score for Pramil is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Pramil may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Pramil may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Pramil low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Pramil We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Pramil usage in lactation
Avoid nursing within the next 3 hours after having taken this drug. Not commercially available in Spain.
Answer by DrLact: About Pramil usage in lactation
Because there is little published experience with Pramil during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
Pramil Possible Effects in Breastfeeding
Pramil 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced Pramil 200 mg given intravenously during labor 10 minutes to 3 hours before delivery for obstetric sedation reduced the sucking behavior of the newborn infants. The number of sucks, sucking pressure and total consumption of artificial feeding from the testing device were reduced substantially.[2] In one small study, women given promethazine with meperidine and Pramil during labor, had the time to lactogenesis II prolonged by 14 hours. Women given meperidine or Pramil without promethazine had lactogenesis II prolonged 7 hours compared to unmedicated women, but the difference was not statistically significant.[3]
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