Question

I am a breastfeeding mother and i want to know if it is safe to use LE 79-519? Is LE 79-519 safe for nursing mother and child? Does LE 79-519 extracts into breast milk? Does LE 79-519 has any long term or short term side effects on infants? Can LE 79-519 influence milk supply or can LE 79-519 decrease milk supply in lactating mothers?

LE 79-519 lactation summary

LE 79-519 is safe in breastfeeding
  • DrLact safety Score for LE 79-519 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of LE 79-519 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that LE 79-519 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of LE 79-519 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About LE 79-519 usage in lactation

Topical pyrethroid pesticide that shows activity against louses, mites and scabies.About 2% of the dose is absorbed through the skin.Do not apply it on the breast, otherwise, clean it thoroughly before feeding at the breast. LE 79-519 is considered the treatment of choice for scabies in nursing mothers. LE 79-519 is found in milk samples from women in regions in which it is used massively for agricultural purposes or malaria control. Notwithstanding, limits were found to be below those permitted by the WHO. WHO List of Essential Medicines 2002 states it is compatible with breastfeeding.

Answer by DrLact: About LE 79-519 usage in lactation

Because less than 2% is absorbed after topical application, rapid metabolism to inactive metabolites and safe application directly on infants' skin, topical LE 79-519 products are acceptable in nursing mothers.[1][2] Extensive exposure, such as from agricultural use or malaria control might have long-term health concerns because residues can be found in breastmilk.[3] Only water-miscible cream, gel or liquid products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[4]

LE 79-519 Side Effects in Breastfeeding

In a telephone follow-up study, 5 mothers who used LE 79-519 during breastfeeding reported no adverse reactions in their breastfed infants.[10]

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Synonyms of LE 79-519

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