Is Penicillin G Procaine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Penicillin G Procaine? Is Penicillin G Procaine safe for nursing mother and child? Does Penicillin G Procaine extracts into breast milk? Does Penicillin G Procaine has any long term or short term side effects on infants? Can Penicillin G Procaine influence milk supply or can Penicillin G Procaine decrease milk supply in lactating mothers?

At latest update on excretion into breast milk of Penicillin procaine published information was not found. Mother plasma levels of Penicillin procaine have been shown to be lower than those of Penicillin G. Penicillin G is excreted into breast milk in non-significant amounts without side-effects observed among breastfed infants from treated mothers. Plasma levels in those infants were shown to be low or undetectable. Penicillin is a broad spectrum antibiotic that is commonly used in Pediatrics and Neonatology with very good tolerance even in premature newborns. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics. Eleventh WHO's Model List of Essential Drugs 2002: Compatible with breastfeeding.

Limited information indicates that penicillin G produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Penicillin G is acceptable in nursing mothers.

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of benzathine penicillin G intramuscularly. However, the baby had also received 10 units of penicillin G at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[5]