Is O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate? Is O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate safe for nursing mother and child? Does O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate extracts into breast milk? Does O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate has any long term or short term side effects on infants? Can O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate influence milk supply or can O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate decrease milk supply in lactating mothers?
O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate lactation summary
- DrLact safety Score for O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate usage in lactation
Because a poor oral absorption it is likely a minimal excretion into breast milk.
Answer by DrLact: About O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate usage in lactation
O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate and its active metabolite are minimally excreted into breastmilk. An informal consultation group to the World Health Organization concluded that a single oral dose of O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate can be given to lactating women.[1]
O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate Side Effects in Breastfeeding
Two mothers with intestinal parasites were given a single 400 mg oral dose of O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate while exclusively breastfeeding their infants who were between 1 and 6 months of age. No mention was made of adverse reactions in the breastfed infants.[3]
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