Is Proheptatriene Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Proheptatriene? Is Proheptatriene safe for nursing mother and child? Does Proheptatriene extracts into breast milk? Does Proheptatriene has any long term or short term side effects on infants? Can Proheptatriene influence milk supply or can Proheptatriene decrease milk supply in lactating mothers?
Proheptatriene lactation summary
- DrLact safety Score for Proheptatriene is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Proheptatriene may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Proheptatriene may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Proheptatriene low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Proheptatriene We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Proheptatriene usage in lactation
Relaxant drug of the muscle with action on the Central Nervous System and chemically related to tricyclic antidepressants. At latest update, relevant information on excretion into breast milk was not found. Because of a high plasma protein binding capacity, excretion into breast milk seems to be unlikely. Long-term treatments or those mothers who are nursing a newborn or premature infant would be prudent the use of a known safer alternative or with a shorter elimination half life. Infants should be monitored for sleepiness.
Answer by DrLact: About Proheptatriene usage in lactation
If Proheptatriene is required by the mother, it is not necessarily a reason to discontinue breastfeeding. However, because there is no published experience with Proheptatriene during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant, or when other drugs that can cause sedation are used simultaneously.
Alternate Drugs
Dantrolene(Unsafe)
Carisoprodol(Low Risk)
Baclofen(Safe)
Meprobamate(Low Risk)
Cyclobenzaprine(Low Risk)