Is Ro 4-1577 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Ro 4-1577? Is Ro 4-1577 safe for nursing mother and child? Does Ro 4-1577 extracts into breast milk? Does Ro 4-1577 has any long term or short term side effects on infants? Can Ro 4-1577 influence milk supply or can Ro 4-1577 decrease milk supply in lactating mothers?
Ro 4-1577 lactation summary
- DrLact safety Score for Ro 4-1577 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Ro 4-1577 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Ro 4-1577 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Ro 4-1577 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Ro 4-1577 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Ro 4-1577 usage in lactation
Relaxant drug of the muscle with action on the Central Nervous System and chemically related to tricyclic antidepressants. At latest update, relevant information on excretion into breast milk was not found. Because of a high plasma protein binding capacity, excretion into breast milk seems to be unlikely. Long-term treatments or those mothers who are nursing a newborn or premature infant would be prudent the use of a known safer alternative or with a shorter elimination half life. Infants should be monitored for sleepiness.
Answer by DrLact: About Ro 4-1577 usage in lactation
If Ro 4-1577 is required by the mother, it is not necessarily a reason to discontinue breastfeeding. However, because there is no published experience with Ro 4-1577 during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant, or when other drugs that can cause sedation are used simultaneously.
Alternate Drugs
Meprobamate(Low Risk)
Cyclobenzaprine(Low Risk)
Dantrolene(Unsafe)
Carisoprodol(Low Risk)
Baclofen(Safe)