Question

I am a breastfeeding mother and i want to know if it is safe to use Differin Gel 0.1%? Is Differin Gel 0.1% safe for nursing mother and child? Does Differin Gel 0.1% extracts into breast milk? Does Differin Gel 0.1% has any long term or short term side effects on infants? Can Differin Gel 0.1% influence milk supply or can Differin Gel 0.1% decrease milk supply in lactating mothers?

Differin Gel 0.1% lactation summary

Differin Gel 0.1% is safe in breastfeeding
  • DrLact safety Score for Differin Gel 0.1% is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Differin Gel 0.1% is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Differin Gel 0.1% does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Differin Gel 0.1% safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Differin Gel 0.1% usage in lactation

Retinoid analogue with similar properties as Tretinoine. It is practically not absorbed by skin hence it cannot achieve significant levels in the milk. Avoid using it on the breast or cleanse it thoroughly before nursing.

Answer by DrLact: About Differin Gel 0.1% usage in lactation

Topical Differin Gel 0.1% has not been studied during breastfeeding. Because it is poorly absorbed after topical application,[1] and blood levels are less than 0.25 mcg/L with long-term use, it is probably a low risk to the nursing infant. Do not apply to the nipple area and ensure that the infant's skin does not come into direct contact with the areas of skin that have been treated. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.