Is (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole? Is (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole safe for nursing mother and child? Does (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole extracts into breast milk? Does (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole has any long term or short term side effects on infants? Can (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole influence milk supply or can (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole decrease milk supply in lactating mothers?
(+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole lactation summary
- DrLact safety Score for (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole usage in lactation
Systemic absorption through skin or vaginal mucosa is not significant. Wash hands thoroughly. Avoid using it it on the breast or cleanse before nursing.
Answer by DrLact: About (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole usage in lactation
Vaginal (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole has not been studied during breastfeeding. About 5.5% of a vaginal dose is absorbed and its plasma half-life is 21 to 24 hours. Because there is no published experience with (+-)-1-((4-(p-Chlorophenyl)-2-((2,6-dichlorophenyl)thio)imidazole during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
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