Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 8076? Is HSDB 8076 safe for nursing mother and child? Does HSDB 8076 extracts into breast milk? Does HSDB 8076 has any long term or short term side effects on infants? Can HSDB 8076 influence milk supply or can HSDB 8076 decrease milk supply in lactating mothers?

HSDB 8076 lactation summary

HSDB 8076 is safe in breastfeeding
  • DrLact safety Score for HSDB 8076 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 8076 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 8076 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 8076 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 8076 usage in lactation

X-ray contrast medium with 49% Iodine. At latest update no published data were found on excretion into breast milk. Because a high molecular weight a significant passage into the breast milk is unlikely. It is used in young infants and neonates. The various Iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk. Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk.Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant.The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination. Most radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait any time to resume nursing.

Answer by DrLact: About HSDB 8076 usage in lactation

Intravenous iodinated contrast media are poorly excreted into breastmilk and poorly absorbed orally so they are not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants. One report of very small amounts of iodine from HSDB 8076 in breastmilk supports this generalization. Guidelines developed by several professional organizations state that breastfeeding need not be disrupted after a nursing mother receives a iodine-containing contrast medium.[1][2][3][4]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.