Is BRN 4155643 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use BRN 4155643? Is BRN 4155643 safe for nursing mother and child? Does BRN 4155643 extracts into breast milk? Does BRN 4155643 has any long term or short term side effects on infants? Can BRN 4155643 influence milk supply or can BRN 4155643 decrease milk supply in lactating mothers?
BRN 4155643 lactation summary
- DrLact safety Score for BRN 4155643 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of BRN 4155643 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that BRN 4155643 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of BRN 4155643 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About BRN 4155643 usage in lactation
Prostaglandin E1 analogue that is used in the prevention of gastroduodenal ulcers associated with the use of NSAIDs and induction of labor and abortion provocation. It is found naturally in milk and colostrum. It is excreted in breast milk in clinically non-significant amount with a very short half-life span. Follow-up for intestinal colic or diarrhea in the infant.
Answer by DrLact: About BRN 4155643 usage in lactation
Mispoprostol is a prostaglandin E1 analogue. Prostaglandin E1 and other prostaglandins appear normally in colostrum and milk.[1] Because of the extremely low levels of BRN 4155643 in breastmilk, amounts ingested by the infant are trivial and would not be expected to cause any adverse effects in breastfed infants. No special precautions are required.
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